This repository hosts the FHIR Implementation Guide (IG) for the USCDI+ Cancer project addressing interoperability needs within the cancer community. It is currently hosting the Clinical Trials Matching IG as demonstrated at the 2026 CMS Connectathon. This IG will support preliminary eligibility screening for clinical trials during care delivery by addressing two exchange patterns:
- Provider-driven clinical trials discovery based on USCDI+ Cancer patient data
- Clinical trial (PI) driven discovery of patients based on USCDI+ Cancer compatible values based on query/response patterns
The resulting IG is to be modeled on other USCDI+ projects, including USCDI+ BH.
- Maintainers: @lturi.onc with support from Next Level Health Innovations, LLC on contract with ONC
- Issues/Discussion: There are no anticipated issues at this time. The draft IG is intended for testing and piloting and uses existing US Core and mCode FHIR Resources and profiles. While there may be profiles or bundles developed, they will be in alignment with existing work.
- License: This project is released under CC0 1.0 Universal.
- Contribution Policy: This initial draft was developed with input from patients, clinicians, researchers, and the FHIR community. Contributions are welcome from any community that may benefit or be affected by this work. The testing team will collect issues and suggestions via GitHub Issues, and from testing partners during Connectathons and other testing events as they may arise. All contributions will be reviewed by the maintainers for alignment with project goals and ONC requirements and triaged appropriately.
- Security Information: The repository contains code to build an IG for proof-of-concept testing and piloting. Piloting will not include production systems or live patient data. Any identified security concerns will be reported to the testing team. In production implementations, the IG will be used by hospital and provider EHRs and similar systems and inherit the security features of those systems.
- Compliance Information: This specification and its reference implementation are tested using standard FHIR validation tools, including the HL7 FHIR Validator and IG Publisher. Conformance is aligned with the US Core Implementation Guide, mCode, and relevant ONC interoperability testing requirements for the Connectathon.
├── CTM/ # Directory containing all Clinical Trials Matching FHIR IG components (currently empty)
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├── irAE/ # Directory containing all irAE FHIR IG components (currently empty)